séminaire du pôle évolution du vivant

"The evolutionary ecology of pathogen-host interactions" - Kurt McKean, University at Albany - vendredi 21 novembre 2014, 11h amphi Monge





The Evolutionary Ecology of Pathogen-Host Interactions:

How do the competing needs of hosts and their pathogens affect resistance and virulence?

Pairwise interactions between hosts and pathogens are the primary determinants of the evolution of host defense and pathogen traits promoting within-host growth and survival and between host transmission. However, if the expression of these traits is negatively correlated (via either pleiotropy or linkage disequilibrium) with other fitness-associated traits then these trade-offs may cause dramatic differences from expected trait values under independence. Trade-offs are often referred to as ‘costs’ and three types of costs may be important secondary determinants of host defense and pathogen virulence. In my talk I will discuss examples from work in my own lab and the labs of others illustrating the importance of such costs in understanding the evolution of host defense and pathogen virulence.

Kurt McKean
University at Albany, USA
[web site]